CSNK1G3

Across TCGA pan-cancer cohorts, CSNK1G3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CSNK1G3 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CSNK1G3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CSNK1G3 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where CSNK1G3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	1.000	0.841	.007	11	view →
HNSC	DFS	Quartile	All	0.864	0.634	.007	10	view →
CCRCC	DFS	Quartile	All	1.000	0.304	.009	6	view →
LUAD	DFS	Quartile	II,III,IV	0.765	0.395	.048	2	view →
PDAC	OS	Tertile	All	0.732	0.875	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CSNK1G3–LSCC (DFS)

Open the LSCC breakdown →