CSNK1G3

Across TCGA cell cohorts, CSNK1G3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,355 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSNK1G3-associated GO terms across cancer lineages are Positive regulation of centrosome duplication, Interkinetic nuclear migration, and Positive regulation of organelle assembly. Each is linked with CSNK1G3 in more than 15 cancer types. Because this analysis shows association rather than direction, both CSNK1G3-to-partner and partner-to-CSNK1G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of centrosome duplication grouped by CSNK1G3-low versus CSNK1G3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1G3→partner) and Y-score (partner→CSNK1G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of centrosome duplication →	+0.100	+0.642	<.001	<.001	2	16
UPPER_AERODIGESTIVE_TRACT	Interkinetic nuclear migration →	+0.115	+0.760	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.063	+0.947	.001	.001	3	14
OVARY	Negative regulation of microtubule depolymerization →	+0.082	+0.572	.004	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of centriole elongation →	+0.117	+0.946	<.001	<.001	3	12
BLOOD_Myeloma	Golgi organization →	+0.065	+1.112	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,355 associations by consensus.

Positive regulation of centrosome duplication by CSNK1G3 expression — LUNG_SCLC

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