CSNK1G3

Across TCGA cell cohorts, CSNK1G3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSNK1G3-associated genes across cancer lineages are NABP2, GABRG1, and UBE2QL1. Each is linked with CSNK1G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1G3-to-partner and partner-to-CSNK1G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NABP2 grouped by CSNK1G3-low versus CSNK1G3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1G3→partner) and Y-score (partner→CSNK1G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NABP2 →	+0.466	+3.215	.009	.009	3	1
LARGE_INTESTINE	GABRG1 →	+0.007	+2.518	.006	.006	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.192	+3.459	<.001	.005	3	1
LARGE_INTESTINE	RNF148 →	+0.422	+3.131	<.001	.008	3	1
OVARY	PTGDR →	+0.051	+4.035	<.001	.003	3	1
OVARY	DAZ2 →	+0.064	+4.222	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

NABP2 by CSNK1G3 expression — LARGE_INTESTINE

Explore this box plot interactively →