CSNK1G2

Across TCGA cell cohorts, CSNK1G2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,579 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSNK1G2-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with CSNK1G2 in more than 18 cancer types. Because this analysis shows association rather than direction, both CSNK1G2-to-partner and partner-to-CSNK1G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by CSNK1G2-low versus CSNK1G2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1G2→partner) and Y-score (partner→CSNK1G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.166	+1.055	<.001	<.001	3	19
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.095	+1.003	.005	.001	3	18
BONE	Electron transport coupled proton transport →	+0.095	+1.003	.005	.001	3	18
BONE	Subtelomeric heterochromatin formation →	+0.140	+1.014	<.001	<.001	3	17
BONE	Cytoplasm protein quality control →	+0.173	+0.915	<.001	<.001	3	16
BONE	Regulation of protein localization to chromatin →	+0.159	+0.881	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,579 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by CSNK1G2 expression — BONE

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