CSNK1G2

Across TCGA cell cohorts, CSNK1G2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSNK1G2-associated genes across cancer lineages are RBP2, INSM2, and TACR3. Each is linked with CSNK1G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1G2-to-partner and partner-to-CSNK1G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBP2 grouped by CSNK1G2-low versus CSNK1G2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1G2→partner) and Y-score (partner→CSNK1G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RBP2 →	+0.044	+4.037	<.001	.004	3	1
BLOOD_Leukemia	INSM2 →	+0.165	+3.769	.002	.008	3	1
BLOOD_Leukemia	TACR3 →	+0.034	+4.060	<.001	.003	3	1
BLOOD_Leukemia	SRY →	+0.022	+3.874	.001	.005	3	1
BLOOD_Leukemia	MORN5 →	+0.208	+3.855	<.001	.007	3	1
LARGE_INTESTINE	TBR1 →	+0.042	+3.555	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

RBP2 by CSNK1G2 expression — BLOOD_Leukemia

Explore this box plot interactively →