Across TCGA patient cohorts, CSNK1E mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK1E-associated genes across cancer lineages are Caspase-7-cleavedD198, MSH2, and MSH6. Each is linked with CSNK1E in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1E-to-partner and partner-to-CSNK1E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1E→partner) and Y-score (partner→CSNK1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+1.076	+2.827	<.001	.035	3	2
UCEC	MSH2 →	-0.365	-2.000	<.001	.032	3	1
UCEC	MSH6 →	-0.385	-3.169	.009	.018	3	1
UCEC	p62 Lck ligand →	+0.299	+2.000	.041	.032	3	1
UCEC	PAI-1 →	+0.372	+3.169	.016	.019	3	1
UCEC	PCNA →	+0.293	+2.700	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

CSNK1E survival (RNA) · tumor vs normal (RNA) · all CSNK1E data types