CSNK1D

Across TCGA patient cohorts, CSNK1D mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK1D-associated genes across cancer lineages are eEF2, GAPDH, and MEK1. Each is linked with CSNK1D in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1D-to-partner and partner-to-CSNK1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CSNK1D-low versus CSNK1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1D→partner) and Y-score (partner→CSNK1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.395	+3.169	.007	.018	3	2
COAD	GAPDH →	+0.563	+2.820	.024	.035	3	2
UCEC	MEK1 →	+0.399	+2.584	.008	.010	3	2
UCEC	PCNA →	+0.296	+2.115	<.001	.017	3	2
UCEC	ATM →	-0.649	-2.321	<.001	.006	3	2
COAD	Caspase-7-cleavedD198 →	+1.475	+2.824	<.001	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

eEF2 by CSNK1D expression — UCEC

Explore this box plot interactively →