CSNK1D

Across TCGA cell cohorts, CSNK1D mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CSNK1D-associated genes across cancer lineages are MMP26, C7orf33, and TPPP2. Each is linked with CSNK1D in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1D-to-partner and partner-to-CSNK1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by CSNK1D-low versus CSNK1D-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1D→partner) and Y-score (partner→CSNK1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MMP26 →	+0.020	+5.022	<.001	.002	3	1
SKIN	C7orf33 →	+0.086	+5.217	<.001	<.001	3	1
SKIN	TPPP2 →	+0.067	+5.217	<.001	<.001	3	1
SKIN	IGFL3 →	+0.761	+4.095	<.001	.009	3	1
SKIN	GALP →	+0.017	+4.415	<.001	.007	3	1
SKIN	SPINK9 →	+0.048	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MMP26 by CSNK1D expression — SKIN

Explore this box plot interactively →