CSNK1A1L

Across TCGA pan-cancer cohorts, CSNK1A1L Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CSNK1A1L data layer compared with 18 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher CSNK1A1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CSNK1A1L expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

SCLC, LUSC, and KIRC are the cancer types where CSNK1A1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.082	0.708	<.001	36	view →
LUSC	OS	Median	III,IV	0.140	0.664	.016	12	view →
KIRC	OS	Median	II,III,IV	0.181	0.696	.042	9	view →
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
READ	DFS	Median	III,IV	0.178	0.769	<.001	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
HNSC	OS	Median	III,IV	0.501	0.746	.008	4	view →
SKCM	OS	Median	All	1.000	0.359	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CSNK1A1L–SCLC (OS)

Open the SCLC breakdown →