CSNK1A1L

Across TCGA patient cohorts, CSNK1A1L mutation is significantly associated with the RNA expression of many other genes, with 1,858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK1A1L-associated genes across cancer lineages are CENPN, DSTNP5, and C17orf98. Each is linked with CSNK1A1L in more than 3 cancer types. Because this analysis shows association rather than direction, both CSNK1A1L-to-partner and partner-to-CSNK1A1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPN grouped by CSNK1A1L-low versus CSNK1A1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1A1L→partner) and Y-score (partner→CSNK1A1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPN →	+0.709	+3.928	<.001	<.001	3	4
READ	DSTNP5 →	+0.071	+3.657	.001	.001	3	3
READ	C17orf98 →	+0.200	+3.019	<.001	.008	3	3
UCEC	GTF2A2 →	+0.488	+4.053	<.001	<.001	3	3
LUAD	HPF1 →	+0.451	+3.459	.002	.005	3	3
UCEC	WBP4 →	+0.361	+1.923	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,858 associations by consensus.

CENPN by CSNK1A1L expression — UCEC

Explore this box plot interactively →