CSNK1A1L

Across TCGA cell cohorts, CSNK1A1L mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CSNK1A1L-associated genes across cancer lineages are MMP27, FSHR, and CCDC195. Each is linked with CSNK1A1L in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1A1L-to-partner and partner-to-CSNK1A1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by CSNK1A1L-low versus CSNK1A1L-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1A1L→partner) and Y-score (partner→CSNK1A1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	FSHR →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	CCDC195 →	+0.043	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.095	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	MBD3L2 →	+0.151	+5.228	<.001	.005	3	1
LARGE_INTESTINE	FEZF2 →	+0.011	+3.103	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MMP27 by CSNK1A1L expression — OESOPHAGUS

Explore this box plot interactively →