CSNK1A1

Across TCGA pan-cancer cohorts, CSNK1A1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CSNK1A1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CSNK1A1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CSNK1A1 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

COAD, HNSC, and UCEC are the cancer types where CSNK1A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	1.000	0.890	.029	36	view →
HNSC	DFS	Quartile	II,III,IV	1.000	0.831	.002	25	view →
UCEC	OS	Tertile	All	1.000	0.889	.012	22	view →
CCRCC	DFS	Median	IV	0.233	1.000	.008	9	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.838	.017	8	view →
PDAC	OS	Median	IV	0.381	0.951	.006	6	view →
LUAD	DFS	Tertile	All	0.654	0.934	.040	4	view →
GBM	DFS	Median	All	0.264	0.455	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CSNK1A1–COAD (DFS)

Open the COAD breakdown →