CSNK1A1

Across TCGA patient cohorts, CSNK1A1 mutation is significantly associated with the RNA expression of many other genes, with 3,864 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK1A1-associated genes across cancer lineages are RN7SKP132, CICP6, and RAB28P3. Each is linked with CSNK1A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSNK1A1-to-partner and partner-to-CSNK1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP132 grouped by CSNK1A1-low versus CSNK1A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1A1→partner) and Y-score (partner→CSNK1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP132 →	+0.055	+2.832	.001	.001	3	3
HNSC	CICP6 →	+0.011	+5.124	.007	.008	3	2
LUSC	RAB28P3 →	+0.184	+5.882	.008	.002	3	2
UCEC	RNU1-1 →	+0.125	+1.702	.005	.007	3	2
UCEC	RNU7-125P →	+0.225	+1.468	.008	.009	3	2
UCEC	IGKV1-37 →	+0.103	+1.886	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,864 associations by consensus.

RN7SKP132 by CSNK1A1 expression — UCEC

Explore this box plot interactively →