CSN2

Across TCGA cell cohorts, CSN2 RNA expression is significantly associated with the mutation status of many other genes, with 143 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSN2-associated genes across cancer lineages are APOB, POGZ, and CYP27C1. Each is linked with CSN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSN2-to-partner and partner-to-CSN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOB grouped by CSN2-low versus CSN2-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN2→partner) and Y-score (partner→CSN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	APOB →	+2.232	+0.018	.001	.005	3	2
LUNG_NSCLC_LUSC	POGZ →	+4.643	+0.023	.008	<.001	3	2
SKIN	CYP27C1 →	+5.415	+0.104	.004	<.001	3	2
SKIN	PFKFB1 →	+4.415	+0.078	.007	<.001	3	2
LARGE_INTESTINE	TGM3 →	+2.777	+0.020	.004	<.001	3	2
LARGE_INTESTINE	NFIX →	+4.099	+0.027	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

APOB by CSN2 expression — LUNG_SCLC

Explore this box plot interactively →