CSN2

Across TCGA cell cohorts, CSN2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CSN2-associated genes across cancer lineages are PRR30 and KRTAP5-3. Each is linked with CSN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSN2-to-partner and partner-to-CSN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR30 grouped by CSN2-low versus CSN2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN2→partner) and Y-score (partner→CSN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PRR30 →	+0.019	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	KRTAP5-3 →	+0.127	+4.734	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PRR30 by CSN2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →