CSMD2-AS1

Across TCGA pan-cancer cohorts, CSMD2-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CSMD2-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher CSMD2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CSMD2-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

KICH, LUSC, and LIHC are the cancer types where CSMD2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUSC	DFS	Tertile	II,III,IV	0.485	0.743	<.001	66	view →
LIHC	OS	Tertile	All	0.548	0.794	.003	45	view →
UVM	OS	Tertile	All	0.218	0.696	.014	36	view →
KIRC	DFS	Tertile	All	0.376	0.654	.010	30	view →
KIRP	OS	Tertile	II,III,IV	0.186	0.781	.007	27	view →
LAML	DFS	Tertile	All	0.204	0.583	.017	18	view →
LUAD	DFS	Tertile	All	0.808	0.648	.019	18	view →
BLCA	OS	Tertile	III,IV	0.141	0.581	.011	18	view →
ESCA	DFS	Tertile	III,IV	0.521	0.251	.025	15	view →
PCPG	DFS	Tertile	All	0.768	0.935	.042	9	view →
ACC	DFS	Tertile	All	0.147	0.559	.044	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

CSMD2-AS1–KICH (DFS)

Open the KICH breakdown →