Across TCGA patient cohorts, CSMD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,689 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CSMD1-associated genes across cancer lineages are SEPTIN3, NEFH, and SYNGR1. Each is linked with CSMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSMD1-to-partner and partner-to-CSMD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSMD1→partner) and Y-score (partner→CSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN3 →	+0.982	+0.331	.002	<.001	3	1
GBM	NEFH →	+1.606	+0.315	<.001	<.001	3	1
GBM	SYNGR1 →	+1.065	+0.397	<.001	<.001	3	1
GBM	APOL4 →	+1.183	+0.286	.002	.001	3	1
GBM	PVALB →	+1.297	+0.444	<.001	<.001	3	1
GBM	AP4S1 →	+0.273	+0.237	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,689 associations by consensus.

Exploration

CSMD1 survival (RNA) · tumor vs normal (RNA) · all CSMD1 data types