Across TCGA patient cohorts, CSMD1 mutation is significantly associated with the RNA expression of many other genes, with 12,462 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CSMD1-associated genes across cancer lineages are C4orf46, MYZAP, and UNG. Each is linked with CSMD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CSMD1-to-partner and partner-to-CSMD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSMD1→partner) and Y-score (partner→CSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	C4orf46 →	+0.501	+2.533	.009	.002	3	7
SCLC	MYZAP →	-1.077	-1.869	.008	.007	3	7
SCLC	UNG →	+0.977	+1.944	.001	.003	3	7
STAD	MRPS7 →	+0.249	+1.750	.001	<.001	3	7
STAD	RAN →	+0.305	+1.988	<.001	<.001	3	7
STAD	ANP32B →	+0.270	+1.485	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,462 associations by consensus.

Exploration

CSMD1 survival (RNA) · tumor vs normal (RNA) · all CSMD1 data types