Across TCGA cell cohorts, CSMD1 mutation is significantly associated with the RNA expression of many other genes, with 2,204 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSMD1-associated genes across cancer lineages are C8orf58, R3HCC1, and NUP50. Each is linked with CSMD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CSMD1-to-partner and partner-to-CSMD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSMD1→partner) and Y-score (partner→CSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C8orf58 →	+0.560	+1.003	<.001	.007	3	5
LARGE_INTESTINE	R3HCC1 →	+0.806	+1.458	<.001	<.001	3	5
LARGE_INTESTINE	NUP50 →	+0.517	+1.244	.001	.001	3	5
BLOOD_Myeloma	GNL3 →	+0.435	+2.944	.005	.007	3	4
SKIN	PSIP1 →	+0.538	+1.306	.008	<.001	3	4
BLOOD_Leukemia	SMO →	+1.004	+1.678	.003	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,204 associations by consensus.

Exploration

CSMD1 survival (RNA) · tumor vs normal (RNA) · all CSMD1 data types