Across TCGA patient cohorts, CSKMT mutation is significantly associated with the RNA expression of many other genes, with 1,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSKMT-associated genes across cancer lineages are H4C7, OR5H4P, and FAM236A. Each is linked with CSKMT in more than 1 cancer types. Because this analysis shows association rather than direction, both CSKMT-to-partner and partner-to-CSKMT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSKMT→partner) and Y-score (partner→CSKMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H4C7 →	+0.272	+2.398	<.001	.007	3	2
STAD	OR5H4P →	+0.174	+4.254	<.001	.008	3	2
BRCA	FAM236A →	+0.066	+8.057	<.001	.005	3	1
BRCA	SLC2AXP1 →	+0.060	+5.259	.001	.007	3	1
BLCA	MIR609 →	+0.306	+4.588	<.001	.008	3	1
UCEC	GUF1 →	+0.552	+3.212	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,048 associations by consensus.

Exploration

CSKMT survival (RNA) · tumor vs normal (RNA) · all CSKMT data types