Across TCGA patient cohorts, CSKMT mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSKMT-associated genes across cancer lineages are eEF2, ETS-1, and MEK1. Each is linked with CSKMT in more than 1 cancer types. Because this analysis shows association rather than direction, both CSKMT-to-partner and partner-to-CSKMT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSKMT→partner) and Y-score (partner→CSKMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.497	+3.321	.008	.010	3	1
UCEC	ETS-1 →	+0.372	+3.000	.025	.036	3	1
UCEC	MEK1 →	+0.503	+2.999	.008	.035	3	1
UCEC	PEA-15_pS116 →	+0.621	+3.321	<.001	.010	3	1
UCEC	PI3K-p85 →	+0.232	+3.009	.034	.019	3	1
UCEC	AMPK_pT172 →	+0.444	+2.183	.039	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

CSKMT survival (RNA) · tumor vs normal (RNA) · all CSKMT data types