CSK

Across TCGA pan-cancer cohorts, CSK RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CSK’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CSK RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CSK is over-expressed in tumor.

KIRC, KIRP, and BLCA are the cancer types where CSK tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSK RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.144	<.001	12	view →
KIRP	Male	II,III,IV	+0.798	<.001	9	view →
BLCA	Male	III,IV	+1.452	<.001	8	view →
STAD	All	II,III,IV	+1.148	<.001	8	view →
LIHC	Female	II,III,IV	+0.754	<.001	8	view →
UCEC	All	III,IV	+1.130	<.001	6	view →
LUSC	All	II,III,IV	+0.686	<.001	6	view →
BRCA	All	All	+0.551	<.001	6	view →
COAD	Female	All	+0.355	.003	4	view →
THCA	All	III,IV	+0.301	.022	4	view →
CHOL	Female	All	+1.549	<.001	3	view →
PRAD	All	All	+0.472	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CSK–KIRC

Open the KIRC breakdown →