CSH1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CSH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 236 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CSH1-associated GO terms across cancer lineages are Regulation by virus of viral protein levels in host cell, Metanephric glomerulus vasculature development, and Positive regulation of ossification. Each is linked with CSH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSH1-to-partner and partner-to-CSH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation by virus of viral protein levels in host cell grouped by CSH1-low versus CSH1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSH1→partner) and Y-score (partner→CSH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaRegulation by virus of viral protein levels in host cell →+0.071+0.024.002.00633
BLOOD_LeukemiaMetanephric glomerulus vasculature development →-0.906-0.013.004.00732
BLOOD_LymphomaPositive regulation of ossification →-0.073-0.028<.001.00132
BLOOD_LymphomaAldehyde catabolic process →+0.101+0.025<.001.00432
BLOOD_LymphomaSkeletal system morphogenesis →-0.041-0.020<.001<.00132
BLOOD_LymphomaPutrescine biosynthetic process →-0.121-0.018<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

Regulation by virus of viral protein levels in host cell by CSH1 expression — BLOOD_Lymphoma

Box plot of Regulation by virus of viral protein levels in host cell in CSH1-low vs CSH1-high samples in BLOOD_Lymphoma.

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Exploration