CSGALNACT2

Across TCGA pan-cancer cohorts, CSGALNACT2 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CSGALNACT2’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where CSGALNACT2 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CSGALNACT2 is over-expressed in tumor.

PDAC, HNSC, and CCRCC are the cancer types where CSGALNACT2 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSGALNACT2 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PDAC	All	All	+0.532	<.001	10	view →
HNSC	Male	III,IV	+0.598	<.001	8	view →
CCRCC	All	II,III,IV	+0.554	<.001	5	view →
LSCC	All	All	+0.141	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CSGALNACT2–PDAC

Open the PDAC breakdown →