CSGALNACT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CSGALNACT2 mutation is significantly associated with the RNA expression of many other genes, with 1,322 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSGALNACT2-associated genes across cancer lineages are SNORA10B, RNA5SP436, and RN7SL478P. Each is linked with CSGALNACT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSGALNACT2-to-partner and partner-to-CSGALNACT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA10B grouped by CSGALNACT2-low versus CSGALNACT2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSGALNACT2→partner) and Y-score (partner→CSGALNACT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCSNORA10B →+0.538+4.150<.001.00333
BLCARNA5SP436 →+0.164+5.048<.001.00233
BRCARN7SL478P →+0.189+4.975.005.00232
HNSCRNA5SP478 →+0.252+5.008<.001.00432
BRCATRDD1 →+0.682+7.473<.001.00732
UCECNDOR1 →+0.403+2.765.005.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,322 associations by consensus.

SNORA10B by CSGALNACT2 expression — LUSC

Box plot of SNORA10B in CSGALNACT2-low vs CSGALNACT2-high samples in LUSC.

Explore this box plot interactively →

Exploration