CSGALNACT2

Across TCGA patient cohorts, CSGALNACT2 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSGALNACT2-associated genes across cancer lineages are PDCD4, Cyclin-B1, and EGFR_pY1068. Each is linked with CSGALNACT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSGALNACT2-to-partner and partner-to-CSGALNACT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by CSGALNACT2-low versus CSGALNACT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSGALNACT2→partner) and Y-score (partner→CSGALNACT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.567	-2.321	.003	.006	3	2
UCEC	Cyclin-B1 →	+0.714	+3.584	.002	.002	3	2
UCEC	EGFR_pY1068 →	-0.272	-2.459	.008	.019	3	1
UCEC	mTOR_pS2448 →	-0.144	-1.980	.019	.030	3	1
UCEC	p21 →	+0.191	+3.013	.016	.018	3	1
UCEC	STAT3_pY705 →	-0.393	-2.212	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

PDCD4 by CSGALNACT2 expression — UCEC

Explore this box plot interactively →