CSGALNACT2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CSGALNACT2 mutation is significantly associated with the RNA expression of many other genes, with 120 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSGALNACT2-associated genes across cancer lineages are CA2, GPR63, and WARS2. Each is linked with CSGALNACT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSGALNACT2-to-partner and partner-to-CSGALNACT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CA2 grouped by CSGALNACT2-low versus CSGALNACT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSGALNACT2→partner) and Y-score (partner→CSGALNACT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECA2 →+1.876+3.212.001.00631
LARGE_INTESTINEGPR63 →+1.035+3.212<.001.00631
LARGE_INTESTINEWARS2 →+0.609+3.212.001.00631
LARGE_INTESTINEGRSF1 →+0.546+3.212.001.00631
LARGE_INTESTINERINT1 →+0.493+3.212.001.00631
LARGE_INTESTINENGLY1 →+0.437+3.064.003.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

CA2 by CSGALNACT2 expression — LARGE_INTESTINE

Box plot of CA2 in CSGALNACT2-low vs CSGALNACT2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration