CSGALNACT2

Across TCGA cell cohorts, CSGALNACT2 mutation is significantly associated with the mutation status of many other genes, with 4,553 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSGALNACT2-associated genes across cancer lineages are CPSF7, ZNF586, and ALCAM. Each is linked with CSGALNACT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSGALNACT2-to-partner and partner-to-CSGALNACT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPSF7 grouped by CSGALNACT2-low versus CSGALNACT2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSGALNACT2→partner) and Y-score (partner→CSGALNACT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CPSF7 →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	ZNF586 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	ALCAM →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	CCDC144A →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	HOXD12 →	+6.014	+6.014	.001	.001	1	2
BLOOD_Lymphoma	USP47 →	+6.014	+6.014	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,553 associations by consensus.

CPSF7 by CSGALNACT2 expression — BLOOD_Lymphoma

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