CSGALNACT1

Across TCGA patient cohorts, CSGALNACT1 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSGALNACT1-associated genes across cancer lineages are Caveolin-1, 4E-BP1, and C-Raf. Each is linked with CSGALNACT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSGALNACT1-to-partner and partner-to-CSGALNACT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveolin-1 grouped by CSGALNACT1-low versus CSGALNACT1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSGALNACT1→partner) and Y-score (partner→CSGALNACT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Caveolin-1 →	-0.782	-3.000	.035	.033	3	2
UCEC	4E-BP1 →	+0.418	+3.999	<.001	<.001	3	2
STAD	C-Raf →	+0.201	+3.000	.010	.033	3	2
STAD	Cyclin-B1 →	+0.754	+3.169	<.001	.019	3	2
UCEC	GSK-3a-b_pS21_S9 →	+0.313	+1.290	.026	.034	3	2
UCEC	INPP4B →	-0.329	-2.502	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Caveolin-1 by CSGALNACT1 expression — STAD

Explore this box plot interactively →