CSF3R

Across TCGA pan-cancer cohorts, CSF3R Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CSF3R data layer compared with 24 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher CSF3R Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CSF3R expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

ESCA, UCEC, and BLCA are the cancer types where CSF3R Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Median	II,III,IV	0.163	0.525	.012	12	view →
UCEC	DFS	Median	All	0.939	0.616	.017	8	view →
BLCA	DFS	Median	All	1.000	0.329	.029	6	view →
COAD	OS	Median	III,IV	0.208	0.791	.008	3	view →
SKCM	OS	Median	IV	0.415	0.861	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CSF3R–ESCA (DFS)

Open the ESCA breakdown →