CSF3

Across TCGA patient cohorts, CSF3 mutation is significantly associated with the RNA expression of many other genes, with 361 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSF3-associated genes across cancer lineages are OR1A2, MIR6821, and FAM230A. Each is linked with CSF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSF3-to-partner and partner-to-CSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1A2 grouped by CSF3-low versus CSF3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF3→partner) and Y-score (partner→CSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR1A2 →	+0.031	+4.771	.007	.006	3	2
BRCA	MIR6821 →	+0.743	+4.243	<.001	.009	3	1
BRCA	FAM230A →	+0.029	+6.038	<.001	.001	3	1
BRCA	LINC00254 →	+0.113	+4.971	<.001	.005	3	1
UCEC	LINC01607 →	-0.748	-3.568	.001	.002	3	1
UCEC	RNA5SP414 →	+0.495	+2.407	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 361 associations by consensus.

OR1A2 by CSF3 expression — SKCM

Explore this box plot interactively →