CSF3

Across TCGA cell cohorts, CSF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 794 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CSF3-associated GO terms across cancer lineages are Negative regulation of cell adhesion molecule production, Positive regulation of angiogenesis, and Luteinizing hormone signaling pathway. Each is linked with CSF3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CSF3-to-partner and partner-to-CSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell adhesion molecule production grouped by CSF3-low versus CSF3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF3→partner) and Y-score (partner→CSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell adhesion molecule production →	+1.146	+1.833	<.001	.009	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of angiogenesis →	+0.095	+2.009	<.001	.002	3	5
OESOPHAGUS	Luteinizing hormone signaling pathway →	+0.985	+0.136	.005	.007	3	5
OESOPHAGUS	Response to transition metal nanoparticle →	-0.256	-0.121	.001	.003	3	4
UPPER_AERODIGESTIVE_TRACT	Urokinase plasminogen activator signaling pathway →	+0.327	+1.907	<.001	<.001	3	4
PANCREAS	Regulation of cell adhesion molecule production →	+1.165	+0.691	<.001	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 794 associations by consensus.

Negative regulation of cell adhesion molecule production by CSF3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →