Across TCGA pan-cancer cohorts, CSF2RBP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CSF2RBP1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CSF2RBP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CSF2RBP1 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.
HNSC, LUAD, and READ are the cancer types where CSF2RBP1 tumor–normal differential expression is most reproducible.