CSF2RB

Across TCGA cell cohorts, CSF2RB mutation is significantly associated with the RNA expression of many other genes, with 122 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CSF2RB-associated genes across cancer lineages are MAGEB4, SLC22A24, and PHOX2B. Each is linked with CSF2RB in more than 1 cancer types. Because this analysis shows association rather than direction, both CSF2RB-to-partner and partner-to-CSF2RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by CSF2RB-low versus CSF2RB-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF2RB→partner) and Y-score (partner→CSF2RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MAGEB4 →	+0.726	+4.459	<.001	.001	3	2
BLOOD_Lymphoma	SLC22A24 →	+0.010	+4.662	<.001	.003	3	2
LUNG_NSCLC_LUAD	PHOX2B →	+0.024	+3.095	.001	.009	3	2
LUNG_NSCLC_LUAD	CYP4X1 →	+0.958	+3.111	<.001	.009	3	2
LUNG_NSCLC_LUAD	CYP4A11 →	+0.010	+2.536	<.001	.007	3	2
KIDNEY	SLC39A12 →	+0.013	+4.121	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 122 associations by consensus.

MAGEB4 by CSF2RB expression — BLOOD_Lymphoma

Explore this box plot interactively →