Across TCGA cell cohorts, CSF2RA mutation is significantly associated with the drug of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSF2RA-associated genes across cancer lineages are Motesanib, PAK_5339, and Savolitinib. Each is linked with CSF2RA in more than 1 cancer types. Because this analysis shows association rather than direction, both CSF2RA-to-partner and partner-to-CSF2RA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF2RA→partner) and Y-score (partner→CSF2RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Motesanib →	+0.346	+2.678	.032	.037	3	1
LARGE_INTESTINE	PAK_5339 →	+0.307	+2.871	.029	.021	3	1
LARGE_INTESTINE	Savolitinib →	+0.403	+2.777	.024	.038	3	1
LARGE_INTESTINE	KIN001-236 →	+0.380	+2.874	.004	.021	3	1
LARGE_INTESTINE	Tenovin-6 →	+0.438	+3.008	.024	.016	3	1
LARGE_INTESTINE	Brivanib →	+0.365	+2.874	.027	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

CSF2RA survival (RNA) · tumor vs normal (RNA) · all CSF2RA data types