CSF2

Across TCGA patient cohorts, CSF2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSF2-associated genes across cancer lineages are GMP, HSC, and Skeletal muscle. Each is linked with CSF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSF2-to-partner and partner-to-CSF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by CSF2-low versus CSF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF2→partner) and Y-score (partner→CSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GMP →	+0.137	+2.612	<.001	.017	3	1
UCEC	HSC →	+0.185	+3.010	.003	.020	3	1
UCEC	Skeletal muscle →	+0.051	+3.010	.044	.020	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GMP by CSF2 expression — UCEC

Explore this box plot interactively →