CSF2

Across TCGA cell cohorts, CSF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,262 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CSF2-associated GO terms across cancer lineages are Regulation of protein maturation, Urokinase plasminogen activator signaling pathway, and Regulation of positive chemotaxis. Each is linked with CSF2 in more than 14 cancer types. Because this analysis shows association rather than direction, both CSF2-to-partner and partner-to-CSF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein maturation grouped by CSF2-low versus CSF2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF2→partner) and Y-score (partner→CSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of protein maturation →	+0.167	+1.486	<.001	<.001	3	15
LIVER	Urokinase plasminogen activator signaling pathway →	+1.310	+1.832	.002	<.001	3	15
LIVER	Regulation of positive chemotaxis →	+0.281	+1.956	<.001	<.001	3	15
LIVER	Positive regulation of positive chemotaxis →	+0.278	+1.956	<.001	<.001	3	15
BREAST	Regulation of protein processing →	+0.172	+1.074	<.001	.002	3	15
LUNG_NSCLC_LUAD	Cellular response to external stimulus →	+0.088	+1.801	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,262 associations by consensus.

Regulation of protein maturation by CSF2 expression — SOFT_TISSUE

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