CSF1R

Across TCGA pan-cancer cohorts, CSF1R Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CSF1R data layer compared with 20 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CSF1R Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CSF1R expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

ACC, LUAD, and CESC are the cancer types where CSF1R Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.046	0.753	<.001	36	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	9	view →
CESC	DFS	Median	All	0.081	0.544	.009	6	view →
KIRP	OS	Median	III,IV	0.176	0.661	.027	3	view →
UCEC	DFS	Median	All	0.925	0.622	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CSF1R–ACC (DFS)

Open the ACC breakdown →