CSF1R

Across TCGA pan-cancer cohorts, CSF1R mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CSF1R data layer compared with 20 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CSF1R mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CSF1R expression acts as an unfavorable survival marker.

LUAD, HNSC, and PDAC are the cancer types where CSF1R mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	III,IV	0.244	0.707	.002	16	view →
HNSC	DFS	Quartile	II,III,IV	0.456	0.840	.001	12	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
CCRCC	OS	Quartile	II,III,IV	0.688	0.991	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CSF1R–LUAD (OS)

Open the LUAD breakdown →