CSF1R

Across TCGA cell cohorts, CSF1R RNA expression is significantly associated with the go_rna of many other GO terms, with 4,174 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSF1R-associated GO terms across cancer lineages are Positive regulation of supramolecular fiber organization, Endoderm formation, and Regulation of protein localization to mitochondrion. Each is linked with CSF1R in more than 9 cancer types. Because this analysis shows association rather than direction, both CSF1R-to-partner and partner-to-CSF1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of supramolecular fiber organization grouped by CSF1R-low versus CSF1R-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF1R→partner) and Y-score (partner→CSF1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of supramolecular fiber organization →	+0.077	+1.006	<.001	<.001	3	10
BONE	Endoderm formation →	+0.140	+1.129	.001	.003	3	10
STOMACH	Regulation of protein localization to mitochondrion →	+0.137	+0.661	<.001	.002	3	10
SOFT_TISSUE	Wound healing →	+0.102	+0.629	<.001	.006	3	10
BONE	Regulation of focal adhesion assembly →	+0.144	+1.213	<.001	.001	3	10
BONE	Regulation of cell-substrate junction assembly →	+0.144	+1.213	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,174 associations by consensus.

Positive regulation of supramolecular fiber organization by CSF1R expression — BONE

Explore this box plot interactively →