Across TCGA patient cohorts, CSF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,972 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CSF1-associated genes across cancer lineages are VSIG4, ITGAM, and FCGBP. Each is linked with CSF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CSF1-to-partner and partner-to-CSF1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF1→partner) and Y-score (partner→CSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VSIG4 →	+0.844	+0.436	<.001	.002	3	4
GBM	ITGAM →	+0.848	+0.575	<.001	.004	3	4
PDAC	FCGBP →	+1.697	+0.633	.001	<.001	3	4
OV	LILRA1 →	+0.459	+0.532	<.001	.007	3	3
BRCA	IGSF21 →	+1.004	+0.462	.006	.006	2	4
OV	SPP1 →	+1.145	+0.539	.007	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,972 associations by consensus.

Exploration

CSF1 survival (RNA) · tumor vs normal (RNA) · all CSF1 data types