Across TCGA cell cohorts, CSF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,521 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CSF1-associated GO terms across cancer lineages are Interleukin-11-mediated signaling pathway, Oncostatin-M-mediated signaling pathway, and Positive regulation of supramolecular fiber organization. Each is linked with CSF1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CSF1-to-partner and partner-to-CSF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF1→partner) and Y-score (partner→CSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Interleukin-11-mediated signaling pathway →	+0.272	+3.544	<.001	<.001	3	16
BONE	Oncostatin-M-mediated signaling pathway →	+0.296	+3.501	<.001	<.001	3	15
BREAST	Positive regulation of supramolecular fiber organization →	+0.085	+2.223	<.001	<.001	3	14
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	+0.216	+1.487	<.001	.005	3	14
SOFT_TISSUE	Viral process →	+0.082	+2.396	<.001	<.001	3	14
SOFT_TISSUE	Negative regulation of cytokine production →	+0.076	+2.607	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,521 associations by consensus.

Exploration

CSF1 survival (RNA) · tumor vs normal (RNA) · all CSF1 data types