Across TCGA cell cohorts, CSF1 mutation is significantly associated with the drug of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSF1-associated genes across cancer lineages are Rapamycin, 630600, and LMP744. Each is linked with CSF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSF1-to-partner and partner-to-CSF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF1→partner) and Y-score (partner→CSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Rapamycin →	+0.464	+2.807	.048	.045	3	1
LARGE_INTESTINE	630600 →	+0.763	+3.064	.005	.009	3	1
LARGE_INTESTINE	LMP744 →	+0.783	+3.064	.009	.009	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.763	+3.061	<.001	.010	3	1
LARGE_INTESTINE	Dinaciclib →	+0.594	+3.061	.009	.010	1	1
LARGE_INTESTINE	Gemcitabine →	+0.789	+2.807	.040	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

CSF1 survival (RNA) · tumor vs normal (RNA) · all CSF1 data types