CSE1L

Across TCGA pan-cancer cohorts, CSE1L Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CSE1L data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CSE1L Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated CSE1L expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, HNSC, and KIRC are the cancer types where CSE1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.298	.001	28	view →
HNSC	DFS	Median	All	0.170	0.627	.024	24	view →
KIRC	OS	Median	All	0.144	0.655	.029	12	view →
LIHC	DFS	Median	II,III,IV	0.044	0.427	<.001	6	view →
SKCM	DFS	Median	II,III,IV	0.562	0.245	.026	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CSE1L–UCEC (DFS)

Open the UCEC breakdown →