CSE1L

Across TCGA pan-cancer cohorts, CSE1L mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CSE1L data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CSE1L mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CSE1L expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where CSE1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.694	0.957	<.001	74	view →
PDAC	DFS	Quartile	All	0.277	0.518	.016	13	view →
HNSC	DFS	Median	All	0.698	1.000	.020	8	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
UCEC	DFS	Quartile	All	0.827	1.000	.015	4	view →
LSCC	OS	Median	II,III,IV	0.857	0.624	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CSE1L–CCRCC (OS)

Open the CCRCC breakdown →