CSDE1

Across TCGA pan-cancer cohorts, CSDE1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CSDE1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CSDE1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CSDE1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and PDAC are the cancer types where CSDE1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	III,IV	1.000	0.328	.024	8	view →
LSCC	DFS	Median	All	0.937	0.608	.021	7	view →
PDAC	OS	Quartile	III,IV	0.881	1.000	.006	7	view →
CCRCC	OS	Median	All	0.654	1.000	.010	6	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.778	.039	4	view →
GBM	OS	Tertile	All	0.651	0.873	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CSDE1–UCEC (OS)

Open the UCEC breakdown →