CSDE1

Across TCGA pan-cancer cohorts, CSDE1 mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CSDE1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CSDE1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CSDE1 is over-expressed in tumor, although a few such as CCRCC and PDAC show the opposite, repressed pattern.

LUAD, LSCC, and CCRCC are the cancer types where CSDE1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSDE1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.324	<.001	9	view →
LSCC	Female	II,III,IV	+0.414	<.001	8	view →
CCRCC	Male	All	−0.205	<.001	7	view →
PDAC	Male	All	−0.224	<.001	6	view →
OV	All	All	+0.328	.002	2	view →
COAD	Male	III,IV	−0.167	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CSDE1–LUAD

Open the LUAD breakdown →