CSDE1

Across TCGA patient cohorts, CSDE1 mutation is significantly associated with the RNA expression of many other genes, with 4,110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSDE1-associated genes across cancer lineages are RN7SL134P, TRBV26, and OR11J5P. Each is linked with CSDE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSDE1-to-partner and partner-to-CSDE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by CSDE1-low versus CSDE1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSDE1→partner) and Y-score (partner→CSDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL134P →	+0.211	+4.179	<.001	.003	3	3
ESCA	TRBV26 →	+0.287	+5.068	<.001	.008	3	2
ESCA	OR11J5P →	+0.128	+5.681	<.001	.003	3	2
READ	NIPA2P2 →	+0.043	+5.096	<.001	.002	3	2
READ	LINC02002 →	+0.047	+4.341	<.001	.007	3	2
READ	CTAG1A →	+0.029	+5.096	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,110 associations by consensus.

RN7SL134P by CSDE1 expression — READ

Explore this box plot interactively →