CSDE1

Across TCGA cell cohorts, CSDE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,824 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSDE1-associated GO terms across cancer lineages are Positive regulation of mRNA processing, Telomeric 3' overhang formation, and Protection from non-homologous end joining at telomere. Each is linked with CSDE1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CSDE1-to-partner and partner-to-CSDE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA processing grouped by CSDE1-low versus CSDE1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSDE1→partner) and Y-score (partner→CSDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of mRNA processing →	+0.118	+0.838	.004	<.001	3	16
LUNG_NSCLC_LUSC	Telomeric 3' overhang formation →	+0.144	+0.964	.005	<.001	2	16
BONE	Protection from non-homologous end joining at telomere →	+0.144	+0.486	.001	.007	3	15
LIVER	Epigenetic regulation of gene expression →	+0.057	+0.558	.002	.009	2	15
LIVER	Negative regulation of gene expression, epigenetic →	+0.062	+0.633	.002	.001	3	14
KIDNEY	Termination of RNA polymerase II transcription →	+0.126	+0.829	.002	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,824 associations by consensus.

Positive regulation of mRNA processing by CSDE1 expression — LIVER

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