CSAG3

Across TCGA patient cohorts, CSAG3 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CSAG3-associated genes across cancer lineages are RPL12P36, LETMD1, and SNORD114-7. Each is linked with CSAG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSAG3-to-partner and partner-to-CSAG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL12P36 grouped by CSAG3-low versus CSAG3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSAG3→partner) and Y-score (partner→CSAG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL12P36 →	+0.108	+3.084	<.001	.003	3	2
SKCM	LETMD1 →	+0.648	+3.198	.002	.009	3	1
UCEC	SNORD114-7 →	+0.632	+5.877	<.001	.001	3	1
UCEC	MIR661 →	+1.155	+4.748	<.001	.003	3	1
UCEC	RNA5SP372 →	+1.072	+4.552	<.001	.005	3	1
UCEC	MIR663B →	+0.565	+4.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

RPL12P36 by CSAG3 expression — SKCM

Explore this box plot interactively →